Table 1

Strength of Evidence grading used in these Guidelines.

Strength of evidence

Question

Meaning


I

Effectiveness

Multiple Randomized Controlled Trials or Systematic Reviews of such studies


Diagnosis

Multiple Randomized Controlled Trials, or Cross-sectional Studies with verification by reference (gold) standard, or Systematic Reviews of such studies


II

Effectiveness

One Randomized Controlled Trial


Diagnosis

One Randomized Controlled Trial, or one Cross-sectional Study with verification by reference (gold) standard


III

Effectiveness

Multiple Controlled nonrandomized Studies or Systematic Reviews of such studies


Diagnosis

Multiple Cross-sectional Studies with incomplete & unbalanced verification with reference (gold) standard


IV

Effectiveness

Other studies


Diagnosis


V

Effectiveness

SOSORT Consensus with more than 90% of agreement


Diagnosis


VI

Effectiveness

SOSORT Consensus with 70 to 89% of agreement


Diagnosis


Questions on Effectiveness (treatment results) and Diagnosis (assessment) have been considered

Negrini et al. Scoliosis 2012 7:3   doi:10.1186/1748-7161-7-3

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